drugset / Trial / NCT05255913
Effectiveness of Nano-silver Fluoride and Silver Diamine Fluoride for Arresting Early Childhood Caries
RandomizedParallel-groupSingle-blindPrevention
Summary
Aim of the study: To evaluate and compare the clinical cariostatic efficacy of NSF with 38% SDF solution after sex and twelve months in arresting ECC lesions. The Null hypothesis will be that no statistically significant difference will be detected between the two groups in the arrest of carious lesions in children with ECC.
Timeline
- Start
- 2022-03-15
- Primary completion
- 2023-07-25
- Completion
- 2023-08-03
Publications
- Quritum M, Abdella A, Amer H, El Desouky LM, El Tantawi M. Effectiveness of nanosilver fluoride and silver diamine fluoride in arresting early childhood caries: a randomized controlled clinical trial. BMC Oral Health. 2024 Jun 18;24(1):701. doi: 10.1186/s12903-024-04406-3.
- Quritum M, Abdella A, Amer H, El Tantawi M. Effect of silver diamine fluoride and nano silver fluoride on oral health-related quality of life of children with early childhood caries: A randomized clinical trial. J Dent. 2024 Mar;142:104878. doi: 10.1016/j.jdent.2024.104878. Epub 2024 Feb 2.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nanosilver | Unknown | — | — |
| Comparator | silver diammine fluoride | Small molecule | 38 % | — |