drugset / Trial / NCT05263778

Cholesterol Lowering Via Bempedoic Acid/Ezetimibe, an ACL-Inhibiting Regimen in Acute Coronary Syndrome Study

NCT05263778

RandomizedParallel-groupQuadruple-blindPrevention

Summary

The overall objective of the Cholesterol Lowering via Bempedoic Acid/Ezetimibe, an ACL-Inhibiting Regimen in Acute Coronary Syndrome ACS (CLEAR ACS) study is to determine the efficacy, safety, and tolerability of bempedoic acid/ezetimibe (BA/E) in a contemporary and real-world population, enriched for older adults, women, and underrepresented racial/ethnic groups, of adults with a recent acute coronary syndrome (ACS) event independent of use of statin therapy before the ACS event.

Timeline

Start
2022-03
Primary completion
2023-06
Completion
2023-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bempedoic acid Small molecule 180 mg Oral
Comparator Ezetimibe Unknown 10 mg Oral