drugset / Trial / NCT05268718

Au-Ag-Cu2O NG With PTT Anti Drug-resistant Microbial Keratitis

NCT05268718

RandomizedParallel-groupSingle-blindTreatment

Summary

This clinical study was conducted to evaluate the efficacy and safety of gold-silver cuprous oxide composite nanogels combined with photothermal therapy system in the treatment of severe drug-resistant bacterial keratitis ineffective by traditional antibiotic treatment in human eyes, and to provide translational applications. Based on the clinical evidence, a more effective and safe innovative treatment plan for corneal diseases has been developed.

Timeline

Start
2021-08-01
Primary completion
2023-12-31
Completion
2024-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Hollow gold and silver alloy cuprous oxide shell nano-shell hydrogel Unknown 26.4 ug/ml Topical
Comparator Voriconazole Small molecule 1 % Topical

Indications