drugset / Trial / NCT05268718
Au-Ag-Cu2O NG With PTT Anti Drug-resistant Microbial Keratitis
RandomizedParallel-groupSingle-blindTreatment
Summary
This clinical study was conducted to evaluate the efficacy and safety of gold-silver cuprous oxide composite nanogels combined with photothermal therapy system in the treatment of severe drug-resistant bacterial keratitis ineffective by traditional antibiotic treatment in human eyes, and to provide translational applications. Based on the clinical evidence, a more effective and safe innovative treatment plan for corneal diseases has been developed.
Timeline
- Start
- 2021-08-01
- Primary completion
- 2023-12-31
- Completion
- 2024-07-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Hollow gold and silver alloy cuprous oxide shell nano-shell hydrogel | Unknown | 26.4 ug/ml | Topical |
| Comparator | Voriconazole | Small molecule | 1 % | Topical |