drugset / Trial / NCT05279586

Secondary Prophylaxis of Hepatic Encephalopathy in Cirrhotic Patients

NCT05279586

Phase 0 Unknown 316 enrolled Madonna Magdy Fahmy
RandomizedParallel-groupOpen-labelOther

Summary

The aim of this study is to compare the efficacy and safety of colistin versus lactulose for secondary prophylaxis of overt hepatic encephalopathy in patients with liver cirrhosis.

Timeline

Start
2022-03
Primary completion
2023-02
Completion
2023-03

Drugs

EvaluationDrugModalityDoseRoute
Comparator Colistin Other / unclassified 1.5e+06 iu Oral
Comparator Lactulose Other / unclassified 30 ml Oral
Comparator Lactulose Other / unclassified 60 ml Oral