drugset / Trial / NCT05288725
Mesenchymal Stem Cell Therapy for Knee Osteoarthritis
RandomizedParallel-groupDouble-blindTreatment
Summary
The study is a multicentered, randomized, double-blinded, placebo-controlled study conducted on the unilateral knee of 120 patients. The study compares the effectiveness of an injection of a mesenchymal stem cell preparation from autologous bone marrow aspirate (BMA) to a corticosteroid control for knee osteoarthritis. WOMAC, VAS pain scores, and MRI will be used for assessment. The study will be conducted at 3 sites in the United States.
Timeline
- Start
- 2022-08
- Primary completion
- 2024-06
- Completion
- 2024-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | NGRM-001 | Cell therapy | — | Other |
| Comparator | Triamcinolone Acetonide | Other / unclassified | — | Other |
| Comparator | Ropivacaine | Other / unclassified | — | — |