DAPSONE GEL7.5%Versus Trichloroacetic Acid 20% ON ACNE VULGARIS

Summary

Acne vulgaris, a chronic inflammatory skin disorder, is one of the most prevalent diseases that effects more than 80% of the population worldwide . A variety of factors such as genetics, hormones, infections, as well as environmental factors have been identified as the causes of acne development . Acne usually generates as a result of blockage in the pilosebaceous unit (including hair follicle, hair shaft, and sebaceous gland) due to the over-produced sebum by sebaceous gland, which further triggers the excessive proliferation of the bacterium Propionibacterium acnes (P. Acnes).

Timeline

Start

2022-09-01

Primary completion

2023-10

Completion

2023-10

Publications

• Atallah DA, Bestawy SR, Abouelmajd SA, Badran AY. Dapsone 7.5% Gel Versus Trichloroacetic Acid Peels. Dermatol Surg. 2026 May 1;52(5):458-463. doi: 10.1097/DSS.0000000000004896. Epub 2025 Oct 3.

Drugs

Indications