Trichloroacetic acid
Trials 14
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 22 trials | ||||||
| Phase 2 | NCT06525870 | Aug 2024 → Sep 2025 overdue | cervical intraepithelial neoplasia | Department of Medical Services Ministry of Public Health of Thailand | Enrolling by invitation | No outcome recorded |
| Phase 2 | NCT00422539 | Mar 2006 → ? | — | Shahid Beheshti University of Medical Sciences | Unknown | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT06188104 | Nov → Dec 2023 | cervical intraepithelial neoplasia | Department of Medical Services Ministry of Public Health of Thailand | Withdrawn | No outcome recorded |
| Phase 44 trials | ||||||
| Phase 4 | NCT04744103 | Sep 2023 | actinic cheilitis | Nova Scotia Health Authority | Withdrawn | No outcome recorded Stop: Enrollment |
| Phase 4 | NCT05471947 | Mar → Dec 2023 | hyperpigmentation of the skin, lentigo | Main Line Center for Laser Surgery | Completed | No outcome recorded |
| Phase 4 | NCT05296460 | Sep 2022 → Oct 2023 | acne | Assiut University | Unknown | No outcome recorded |
| Phase 4 | NCT03153852 | Mar 2018 → Dec 2019 | hyperpigmentation of the skin | Assiut University | Unknown | No outcome recorded |
| Phase not applicable7 trials | ||||||
| — | NCT06836791 | Mar 2023 → Oct 2024 | — | Youssef Zaki | Completed | No outcome recorded |
| — | NCT07028567 | Jan → Jun 2023 | skin atrophy | Tanta University | Completed | No outcome recorded |
| — | NCT04889703 | Dec 2022 → Dec 2023 | rosacea | University of Texas Southwestern Medical Center | Withdrawn | No outcome recorded |
| — | NCT06008327 | Aug 2022 → Jun 2023 | acanthosis nigricans | Jinnah Postgraduate Medical Centre | Completed | No outcome recorded |
| — | NCT04911075 | Apr → Oct 2021 | cervical intraepithelial neoplasia | Indonesia University | Completed | No outcome recorded |
| — | NCT05594316 | May 2019 → Aug 2022 | alopecia areata | Al-Azhar University | Completed | No outcome recorded |
| — | NCT02905903 | Feb 2016 → May 2018 | hyperpigmentation of the skin | Henry Ford Health System | Completed | No outcome recorded |
| Comparator or background therapy12 trials | ||||||
| Phase 1 | NCT02892071 Comparator | Dec 2020 → Sep 2022 | hyperpigmentation of the skin | SUZAN OBAGI | Withdrawn | No outcome recorded |
| Phase 2 | NCT04429308 Comparator | Aug 2026 → Dec 2027 expected | actinic keratosis | Northwestern University | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT04485091 Background | Oct 2021 → Jan 2022 | skin atrophy | University of Nove de Julho | Unknown | No outcome recorded |
| Phase 2/3 | NCT06281353 Background | Aug 2022 → Sep 2023 | anogenital human papillomavirus infection | Indonesia University | Completed | No outcome recorded |
| Phase 3 | NCT03071549 Comparator | Apr → Aug 2016 | acne | Cairo University | Completed | No outcome recorded |
| Phase 4 | NCT04823520 Comparator | Apr 2021 → Apr 2022 | hyperpigmentation of the skin | Assiut University | Unknown | No outcome recorded |
| Phase 4 | NCT03475524 Background | Apr 2019 → Aug 2021 | hyperpigmentation of the skin | Assiut University | Unknown | No outcome recorded |
| Phase 4 | NCT03625960 Comparator | Jun 2006 → Jun 2007 | anogenital human papillomavirus infection | Wayne State University | Completed | No outcome recorded |
| — | NCT07060157 Comparator | Jul 2025 → Aug 2026 overdue | hyperpigmentation of the skin | Assiut University | Not yet recruiting | No outcome recorded |
| — | NCT05622916 Comparator | Nov 2022 → Feb 2023 | anogenital human papillomavirus infection | Hasanuddin University | Unknown | No outcome recorded |
| — | NCT05712811 Comparator | Jun → Nov 2022 | common wart | Combined Military Hospital Abbottabad | Completed | No outcome recorded |
| — | NCT05712837 Comparator | Jun → Nov 2022 | acne | Combined Military Hospital Abbottabad | Completed | No outcome recorded |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 29 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | trichloroacetic acid | “Chemical peels consists of a combination of Jessner's Solution: Composed of Salicylic Acid (14%), Medical Grade Lactic Acid (14%), Medical Grade Resorcinol (14%), Denatured...” NCT04429308 ↗25“Efficacy of Topical 85%Trichloroacetic Acid in the Treatment of Low-grade Squamous Intraepithelial Lesion (LSIL) After Low-grade Abnormality of Screening Test: a Randomized...” NCT06525870 ↗ “Trichloroacetic acid (TCA), salicylic acid (SA), and azelaic acid (AA) have proved efficacy in the treatment of acne as a result of their exfoliative and keratolytic properties .” NCT05296460 ↗ “Trichloroacetic acid (TCA) is an acetic acid analogue, which has long been known as a chemical peel and also frequently used to treat genital ward and precancerous skin lesions.” NCT04911075 ↗ “Application of chemical peel of 20% trichloroacetic acid solution (TCM) in association with photobiomodulation (PBM) with red spectrum LED (660nm) on the back of the hands.” NCT04485091 ↗ “The most commonly used peeling agents are alpha-hydroxy-acids, glycolic acid, Jessner solution, salicylic acid, trichloroacetic acid (TCA), pyruvic acid and phenol .” NCT04823520 ↗ “Trichloroacetic Acid as a Topical Treatment for Actinic Cheilitis.” NCT04744103 ↗ “Trichloroacetic Acid (TCA) is a versatile peeling agent” NCT07060157 ↗ “using Trichloroacetic acid (TCA), 35% solution.” NCT02905903 ↗ “22% trichloroacetic acid (TCA) deep medium peel” NCT02892071 ↗ “trichloroacetic acid 90% (applicator method)” NCT05712811 ↗ |
| Known as | NSC-215204 | ChEMBL registry synonym — accepted as the source's own label CHEMBL14053 ↗ |
| Known as | TCA | “OBJECTIVE: To evaluate the efficacy and safety of systemic metformin (1,000 mg and 500 mg) combined with trichloroacetic acid (TCA) peeling versus TCA alone in the treatment of melasma.” PMID 38416809 ↗ Feb 202411“Trichloroacetic acid (TCA), salicylic acid (SA), and azelaic acid (AA) have proved efficacy in the treatment of acne as a result of their exfoliative and keratolytic properties .” NCT05296460 ↗ “Trichloroacetic acid (TCA) is an acetic acid analogue, which has long been known as a chemical peel and also frequently used to treat genital ward and precancerous skin lesions.” NCT04911075 ↗ “trichloroacetic acid (TCA), a superficial chemical exfoliative agent has shown efficacy in treating acanthosis nigricans” NCT06008327 ↗ “To determine the efficacy and HPV clearance of an application of 85% TCA compared to placebo in the treatment of LSIL.” NCT06525870 ↗ “Patients received painting chemical reconstruction of skin scars (CROSS) trichloroacetic acid (TCA) technique.” NCT07028567 ↗ “a 15% trichloroacetic acid (TCA) + 3% glycolic acid (GA) combination peel” PMID 38460193 ↗ Mar 2024 “Trichloroacetic Acid (TCA) is a versatile peeling agent” NCT07060157 ↗ “22% trichloroacetic acid (TCA) deep medium peel” NCT02892071 ↗ “15% Trichloroacetic acid (TCA) chemical peel” NCT04889703 ↗ “Tricholoacetic Acid (TCA)” NCT02905903 ↗ |
| Known as | Tcaa | ChEMBL registry synonym — accepted as the source's own label CHEMBL14053 ↗ |
| Known as | TCM | “Application of chemical peel of 20% trichloroacetic acid solution (TCM) in association with photobiomodulation (PBM) with red spectrum LED (660nm) on the back of the hands.” NCT04485091 ↗ |
| Known as | Trichloroacetate | ChEMBL registry synonym — accepted as the source's own label CHEMBL14053 ↗ |
| Known as | Trichloroethanoic acid | ChEMBL registry synonym — accepted as the source's own label CHEMBL14053 ↗ |
| Known as | Tricholoacetic Acid | “Tricholoacetic Acid (TCA)” NCT02905903 ↗ |
| Modality | Small molecule | “It is a traditional chemical substance which has been used for both superficial and medium-depth as well as deep peelings.” NCT03153852 ↗ |
| Route | Topical | “applying 4 concentrations of TCA (20%, 25%, 30%, 35%) to the buttocks” NCT02905903 ↗ |