drugset / Trial / NCT06008327

Comparison Of Outcome Of Treatment OF Topical 15%TCA VS Topical 0.05% Tretinoin In Treatment Of Acanthosis Nigricans

NCT06008327

Completed 80 enrolled Jinnah Postgraduate Medical Centre
RandomizedParallel-groupOpen-labelTreatment

Summary

Acanthosis nigricans (AN) is a dermatosis with aesthetic implications and is characterized by the focal or diffuse development of a velvety, hyperpigmented cutaneous thickening in intertriginous areas. Trichloroacetic acid (TCA), a superficial chemical exfoliative agent has shown efficacy in treating acanthosis nigricans. Data from this would help in establishing it as a treatment of choice thereby lead to reduction in cost and benefit the patient both financially and psychologically.

Timeline

Start
2022-08-01
Primary completion
2023-06-20
Completion
2023-06-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Tretinoin Small molecule 0.05 % Topical
Subject Trichloroacetic acid Small molecule 15 % Topical

Indications