drugset / Trial / NCT05311813

Safety and Efficacy of Enoxaparin and Hydroxychloroquine in COVID-19

NCT05311813

Completed 200 enrolled Beni-Suef University
RandomizedParallel-groupOpen-labelTreatment

Summary

In this randomized controlled study, two hundred patients with positive PCR and laboratory confirmed COVID-19 will be classified randomly into four groups. The first group is the control group and will be given the conventional treatment of covid-19 only. The second group will be given enoxaparin plus the conventional treatment of Covid-19. The third group will be given hydroxychloroquine (HCQ 400 mg/day) for five days plus the conventional treatment of covid-19. The last group will be given combined therapy of HCQ 400 mg/day and enoxaparin plus the conventional therapy of covid-19 The efficacy will be assessed by the time of undetectable viral RNA, duration of treatment and length of hospital stay. The safety will be assessed by measuring the severity of side effects by following up the patients after treatment.

Timeline

Start
2021-06-01
Primary completion
2021-12-01
Completion
2021-12-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Enoxaparin sodium Other / unclassified 40 mg Subcutaneous
Comparator Hydroxychloroquine Small molecule 400 mg

Indications