drugset / Trial / NCT05320393

Study to Demonstrate Safety and Duration of Effect of 40 Units of PrabotulinumtoxinA-xvfs to Treat Glabellar Lines

NCT05320393

Phase 2 Completed 154 enrolled Evolus, Inc. ethica Clinical Research Inc. · collab
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to demonstrate the safety and duration of effect of 40 Units of prabotulinumtoxinA-xvfs (Jeuveau®) in providing temporary improvement in the appearance of moderate to severe glabellar lines (frown lines, which are the vertical lines that develop between the eyebrows) in adult participants. It will also determine if the duration of effect of 40 Units of Jeuveau® is greater than that of 20 Units of Jeuveau® and 20 Units of Botox® Cosmetic.

Timeline

Start
2022-03-30
Primary completion
2023-05-22
Completion
2023-05-22

Drugs

EvaluationDrugModalityDoseRoute
Comparator Botulinum toxin type A Protein / enzyme biologic 20 iu
Comparator PrabotulinumtoxinA Protein / enzyme biologic 20 iu
Comparator PrabotulinumtoxinA Protein / enzyme biologic 40 iu

Indications

No indication recorded.