drugset / Trial / NCT05321940

Safety Trial of STING-dependent Activators and Stimulated Dendritic Cells for Aggressive Relapsed/Refractory Leukemias

NCT05321940

Phase 1 Withdrawn Juan C. Ramos, MD
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this research is to investigate whether the combination of STING-dependent Adjuvants (STAVs) and dendritic cell (DC) vaccine therapies will increase the body's ability to fight aggressive relapsed or refractory leukemias.

Timeline

Start
2023-11-30
Primary completion
2025-11-30
Completion
2026-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject DC vaccine Vaccine 1.5e+07 cells Intravenous
Subject DC vaccine Vaccine 2e+07 cells Intravenous
Subject STING-Dependent Activators (STAVs) Loaded Autologous Leukemic Cells Cell therapy 5 ml Intravenous