drugset / Trial / NCT05322447

High-dose L-Carnitine and Diaphragmatic Function Assessed by Ultrasonography in Patients With Respiratory Failure.

NCT05322447

Phase 4 Completed 60 enrolled Ain Shams University
RandomizedParallel-groupDouble-blindTreatment

Summary

L-Carnitine supplementation has been shown to boost muscular performance in several studies. In hemodialysis patients with muscular weakness, fatigue, or cramps/aches, after L-carnitine treatment, about two-thirds of patients had at least some improvement in muscular symptoms . L-Carnitine was also found to improve the left ventricular ejection fraction (LVEF) in hemodialysis patients with cardiac morbidity who had significantly reduced LVEF in echocardiography before supplementation. Moreover, L-Carnitine has been shown to improve muscular function and exercise performance in athletes in several studies

Timeline

Start
2022-04-15
Primary completion
2022-08-04
Completion
2022-10-01

Drugs

EvaluationDrugModalityDoseRoute
Subject L-carnitine Other / unclassified 6 g Intravenous
Subject L-carnitine Other / unclassified 18 g Intravenous

Indications