Study of Megestrol Acetate in Grade 2 Endometrioid Endometrial Cancer

Summary

This is a single centre, single arm, open label, preoperative window of opportunity study. Grade 2 endometrioid endometrial carcinoma patients awaiting surgery will be prospectively recruited to receive a pre-operative progestin therapy course. Therapy response will be histologically evaluated and correlated with clinical and molecular data by comparison of responders vs. non-responders pre- and post-treatment tumor samples.

Timeline

Start

2022-07-05

Primary completion

2023-10-12

Completion

2023-10-12

Drugs

Indications