Postoperative Analgesia in Patients Undergoing Elective Lumbar Fusion Operations Under General Anesthesia

Summary

It was proven that intrathecal opioids are considered as an effective means of pain control in several major surgical interventions including spine surgeries. Intrathecal morphine added to a spinal anesthesia reduces acute pain after spine surgeries but has side effects, including dose dependent respiratory depression, nausea, vomiting, pruritus, and sedation. Ultrasound guided Erector Spinae Plane Block (ESPB) was first described in 2016.Recent case reports suggest a positive effect of ultrasound guided ESPB on pain for multiple indications including lumbar spine fusion and scoliosis surgery, with a very low risk of complications as there are no structures in close proximity at risk of needle injury.

Timeline

Start

2022-05-10

Primary completion

2024-09-30

Completion

2024-09-30

Publications

• Ashoor TM, Abdelaal HAS, Elewa GEM, Esmat IM, Rabie AH, Ibrahim AIS, Mohamed AK. Comparison of ultrasound-guided erector spinae plane block to intrathecal morphine for postoperative analgesia in patients undergoing elective lumbar fusion operations under general anesthesia: a randomized controlled trial. BMC Anesthesiol. 2026 Jul 17;26(1):430. doi: 10.1186/s12871-026-04030-4.

Drugs

Indications

No indication recorded.