drugset / Trial / NCT05340504
Evaluating the Hypothesized Mechanism of Action of N-acetylcysteine for Bipolar Disorder
RandomizedCrossoverTriple-blindTreatment
Summary
This research study evaluates the effects of anFDA-approved medication NAC in individuals with Bipolar Disorder. Participants in the study will will be assigned to two medication conditions and will take both NAC and a matched placebo. The order in which they take each medication will be random. Study medication will be taken for 14 days. There will be 5 study visits, with 2 MRI brain imaging scans completed. Questionnaires and clinical interview measures will be completed at study visits along with consistent assessment of potential side effects from study medication.
Timeline
- Start
- 2022-05-13
- Primary completion
- 2023-06-21
- Completion
- 2023-06-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | N-acetylcysteine | Small molecule | — | — |