drugset / Trial / NCT05340504

Evaluating the Hypothesized Mechanism of Action of N-acetylcysteine for Bipolar Disorder

NCT05340504

RandomizedCrossoverTriple-blindTreatment

Summary

This research study evaluates the effects of anFDA-approved medication NAC in individuals with Bipolar Disorder. Participants in the study will will be assigned to two medication conditions and will take both NAC and a matched placebo. The order in which they take each medication will be random. Study medication will be taken for 14 days. There will be 5 study visits, with 2 MRI brain imaging scans completed. Questionnaires and clinical interview measures will be completed at study visits along with consistent assessment of potential side effects from study medication.

Timeline

Start
2022-05-13
Primary completion
2023-06-21
Completion
2023-06-21

Drugs

EvaluationDrugModalityDoseRoute
Subject N-acetylcysteine Small molecule