drugset / Trial / NCT05340803
Sedation of Ventilated Traumatic Brain Injury Patients With Midazolam Alone Versus Combination With Dexmedetomidine or Magnesium Sulfate; Monitored by Ultrasonograghic Optic Nerve Sheath Diameter
RandomizedParallel-groupDouble-blindSupportive care
Summary
In TBI, there is a strong correlation between increased ICP and bad outcome. So, appropriate monitoring can be the gold standard in management of TBI. ICP can be measured by invasive and noninvasive methds. One of these noninvasive methods is bedside measurement of optic nerve sheath diameter (ONSD) by ocular ultrasonography
Timeline
- Start
- 2022-11-01
- Primary completion
- 2025-01-01
- Completion
- 2025-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexmedetomidine | Other / unclassified | — | — |
| Comparator | Magnesium Sulfate | Other / unclassified | — | — |
| Comparator | Midazolam | Small molecule | — | — |