HPI Algorithm for the Prevention of IOH During Spinal Surgery [HPIFPIOH]

Completed 85 enrolled Attikon Hospital

RandomizedParallel-groupTriple-blindPrevention

Summary

The aim of this study is to investigate the hypothesis that the use of the Hypotension Prediction Index algorithm (HPI) can reduce intraoperative hypotension (IOH) in adult patients undergoing spinal surgery in the prone position under general anesthesia, as well as to explore its effect on in-hospital postoperative morbidity and mortality.

Timeline

Start: 2022-05-11
Primary completion: 2023-11-04
Completion: 2024-10-10

Publications

Pilakouta Depaskouale MA, Archonta SA, Moutafidou SKappa, Paidakakos NA, Dimakopoulou AN, Matsota PK. Effectiveness of hypotension prediction index software in reducing intraoperative hypotension in prolonged prone-position spine surgery: a single-center clinical trial. J Clin Monit Comput. 2025 Oct;39(5):875-887. doi: 10.1007/s10877-025-01303-0. Epub 2025 May 23.

Drugs

Evaluation	Drug	Modality	Dose	Route
Background	Noradrenaline	Unknown	—	—
Background	Phenylephrine	Small molecule	—	—

Indications

No indication recorded.