drugset / Trial / NCT05343572

Bone Marrow Derived Stem Cells Mobilization for Treatment of Abnormal Endometrium

NCT05343572

Phase 0 Recruiting 90 enrolled Hugh Taylor
NaSingle-groupOpen-labelTreatment

Summary

This study will assess the use of autologous bone marrow stem cells mobilization using 1,1'-\[1,4-phenylenebis-(methylene)\]-bis-1,4,8,11-tetraazacyclotetradecane (PLERIXAFOR) as an effective medical therapy for the treatment of Asherman's Syndrome (AS), Atrophic Endometrium (AE) and Recurrent Implantation Failure (RIF).

Timeline

Start
2023-11-01
Primary completion
2026-12
Completion
2027-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Plerixafor Small molecule 0.24 mg/kg Subcutaneous
Subject Plerixafor Small molecule 20 mg Subcutaneous