Remimazolam in the Extraction of Impacted Wisdom Teeth

Summary

Benzodiazepines, represented by midazolam, are often used for sedation in outpatient surgery in dentistry. However, midazolam has the problems of slow consciousness recovery and long recovery time, which brings trouble to the patients. Remimazolam is a new type of ultra short acting sedative anesthetic. Compared with other similar products, remimazolam has faster effect, rapid metabolism and has no accumulation, which may mean that compared with midazolam, remimazolam has a better clinical application prospect in dental outpatient surgery.

Timeline

Start

2022-04-18

Primary completion

2023-04-01

Completion

2023-10-01

Publications

• Jing Q, Wang W, Wu L, Wang L, Yuan B, Wang Y, Wang C, Liu L, Guan L, Yu R, Zhang Y, Sessler DI, Huang Y, Wan K, Pei L. A Comparison of the Effect of Remimazolam and Midazolam on Recovery and Preserved Memory Function for Patients with Dental Extraction Anxiety. Drug Des Devel Ther. 2025 Dec 30;19:11977-11987. doi: 10.2147/DDDT.S551322. eCollection 2025.
• Wang L, Jing Q, Pei L, Li M, Ruan X, Chen S, Zhang Y, Wan K, Huang Y. Efficacy of continuous intravenous remimazolam versus midazolam in the extraction of impacted wisdom teeth: protocol of a randomised controlled trial. BMJ Open. 2023 Apr 25;13(4):e067908. doi: 10.1136/bmjopen-2022-067908.

Drugs

Indications