drugset / Trial / NCT05351541
Psilocybin Therapy for Chronic Low Back Pain
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This study evaluates whether psilocybin therapy helps patients cope with chronic low back pain more effectively. Patients may be recruited at Stanford and University of California San Francisco (UCSF), study procedures will occur at UCSF. Each participant will receive a dose of psilocybin with possibly one or more other drugs. Participants will undergo two preparation sessions, a dosing session, three integration sessions to discuss their psilocybin experience, and several follow up sessions.
Timeline
- Start
- 2023-12-01
- Primary completion
- 2026-07
- Completion
- 2026-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Modafinil | Small molecule | — | Oral |
| Subject | Psilocybin | Other / unclassified | 1 mg | Oral |
| Subject | Psilocybin | Other / unclassified | 30 mg | Oral |
| Subject | Zolpidem | Small molecule | — | Oral |