drugset / Trial / NCT05354102

A First-in-human (FIH) Combination Treatment Study With a Single Dose Level of BMC128

NCT05354102

Phase 1 Unknown 11 enrolled Biomica Ltd.
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the safety and tolerability of BMC128 in combination with nivolumab (a known immunotherapy) in order to investigate if administration of select elements of the intestinal microbiome may serve as a novel and effective means of improving the efficacy of anti-cancer immunotherapies.

Timeline

Start
2022-05-01
Primary completion
2024-05
Completion
2025-11

Drugs

EvaluationDrugModalityDoseRoute
Subject BMC128 Other / unclassified Oral
Background Nivolumab Monoclonal antibody 480 mg