drugset / Trial / NCT05367206

Neoadjuvant Chemotherapy Followed by Chemoradiation Versus Chemoradiation for Stage IIIC Cervical Cancer Patients: A Randomized Phase III Trial

NCT05367206 ↗

Phase 3 Recruiting 280 enrolled Sun Yat-sen University
RandomizedParallel-groupOpen-labelTreatment

Summary

Evaluate the efficacy and safety of neoadjuvant chemotherapy (NAC) with albumin-bound paclitaxel and carboplatin followed by chemoradiation therapy (CRT) for stage IIIC cervical cancer patients with carcinoma \>4 cm in greatest dimension and/or lymph node \>2cm in short axis.

Timeline

Start
2022-03-14
Primary completion
2024-03-31
Completion
2027-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule — —
Subject Paclitaxel Small molecule 260 mg/m2 —

Indications