drugset / Trial / NCT05367479
Antibiotics, Gastric Bypass, and the Microbiome
RandomizedParallel-groupOpen-labelBasic science
Summary
This study randomizes patients to two commonly used peri-procedural antibiotics after gastric bypass with the pre and post-operative collection of stool samples, to identify significant differences in relative abundances of gut microbiota phyla, genera and species between the two antibiotic groups used. Gastric bypass may beneficially affect hypertension by altering the post-operative microbiome and specific antibiotics can further enhance the resolution rate by improving microbial diversity and richness.
Timeline
- Start
- 2018-07-18
- Primary completion
- 2020-01-09
- Completion
- 2020-01-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cefazolin | Small molecule | — | Intravenous |
| Subject | Clindamycin | Unknown | — | Intravenous |