drugset / Trial / NCT05371301

Efficacy of Primary Debulking Surgery Versus Neoadjuvant Chemotherapy in Stage IV Ovarian Cancer

NCT05371301 ↗

Phase 3 Unknown 200 enrolled Fudan University
Non-randomizedParallel-groupOpen-labelTreatment

Summary

Epithelial ovarian cancer is mostly diagnosed at late stage (III/IV), and the standard treatment for ovarian cancer includes primary debulking surgery and platinum-based adjuvant chemotherapy. However, scholars suggest that neoadjuvant chemotherapy can be used to reduce the tumor load and control the patient's condition. The aim of this study is to verify the efficacy of primary debulking surgery versus neoadjuvant chemotherapy.

Timeline

Start
2021-07-16
Primary completion
2022-12
Completion
2023-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule 5 unknown Intravenous
Subject Paclitaxel Small molecule 175 mg/m2 Intravenous

Indications