drugset / Trial / NCT05386433
Paxlovid in the Treatment of COVID-19 Patients With Uremia
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is a single-center, open-label, randomized controlled clinical study to evaluate the effect of Paxlovid on the virus-negative time and disease progression in uremic patients infected with SARS-CoV-2 (omicron variants). This study will enroll maintenance hemodialysis patients infected with SARS-CoV-2 (omicron variants). After signing the informed consent form, the qualified subjects will be randomly stratified 1:1 to standard-of-care (SOC) or SOC plus Paxlovid for five days.
Timeline
- Start
- 2022-06
- Primary completion
- 2022-07
- Completion
- 2022-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nirmatrelvir | Small molecule | — | — |
| Background | Ritonavir | Other / unclassified | — | — |