drugset / Trial / NCT05386433

Paxlovid in the Treatment of COVID-19 Patients With Uremia

NCT05386433

Phase 0 Unknown 40 enrolled Ruijin Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is a single-center, open-label, randomized controlled clinical study to evaluate the effect of Paxlovid on the virus-negative time and disease progression in uremic patients infected with SARS-CoV-2 (omicron variants). This study will enroll maintenance hemodialysis patients infected with SARS-CoV-2 (omicron variants). After signing the informed consent form, the qualified subjects will be randomly stratified 1:1 to standard-of-care (SOC) or SOC plus Paxlovid for five days.

Timeline

Start
2022-06
Primary completion
2022-07
Completion
2022-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Nirmatrelvir Small molecule
Background Ritonavir Other / unclassified

Indications