Evaluation Freethiadine Tolerance in Healthy Subjects and Patients With Chronic Hepatitis B, Pharmacokinetics Characteristics and Antiviral Activity of Ⅰ Phase of Study

Summary

The Safety, Tolerability, Pharmacokinetics and antiviral activity Study of Anti hepatitis B virus treatment drug Freethiadine in Healthy subjects and in patients with chronic hepatitis B

Timeline

Start

2021-10-11

Primary completion

2023-01-17

Completion

2023-01-17

Publications

• Li X, Xu J, Sun J, Liu J, Wu M, Zhang H, Zhu X, Li C, Zhang Y, Zhu J, Chen Y, Luo L, He Q, Zhuang Y, Chen Y, Niu J, Ding Y. Safety, Pharmacokinetics and Antiviral Efficacy of Capsid Assembly Modulator Freethiadine in Healthy Volunteers and Chronic Hepatitis B Patients. Liver Int. 2025 Jan;45(1):e16213. doi: 10.1111/liv.16213.

Drugs

Indications