Comparison of Remimazolam With Flumazenil vs. Propofol During RFCA for Atrial Fibrillation

Completed 54 enrolled Seoul National University Hospital

RandomizedParallel-groupTriple-blindTreatment

Summary

This prospective randomized trial aims to compare recovery time from discontinuation of remimazolam followed by flumazenil administration vs. propofol total intravenous anesthesia as the main general anesthetics during radiofrequency catheter ablation treatment of atrial fibrillation.

Timeline

Start: 2022-08-02
Primary completion: 2023-04-25
Completion: 2023-04-25

Publications

Lee S, Lee J, Hwang SY, Ju JW, Nam K, Ahn HJ, Lee SR, Choi EK, Jeon Y, Cho YJ. Remimazolam-flumazenil provides fast recovery from general anesthesia compared to propofol during radiofrequency catheter ablation of atrial fibrillation. Sci Rep. 2024 Jun 3;14(1):12660. doi: 10.1038/s41598-024-63578-8.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Flumazenil	Small molecule	—	—
Comparator	Propofol	Small molecule	—	Intravenous
Subject	Remimazolam	Small molecule	—	—

Indications

No indication recorded.