Induction FOLFIRINOX Followed by Chemoradiation in Locally Advanced Pancreatic Cancer

Summary

There is no a clear consensus regarding the optimal treatment strategy of locally advanced pancreatic cancer. There is a potential role for neoadjuvant therapy to treat micrometastatic disease with chemotherapy, as well as for the treatment of local disease with radiotherapy. The investigators evaluated the safety and efficacy of induction FOLFIRINOX followed by a high weekly dose of gemcitabine concurrent to radiation therapy in patients with borderline resectable and unresectable locally advanced pancreatic cancer (LAPC).

Timeline

Start

2016-07-01

Primary completion

2022-04-01

Completion

2022-06-01

Drugs

Indications