drugset / Trial / NCT05406700

Niraparib In Recurrent IDH 1/2 Gliomas

NCT05406700

Phase 0 Active not recruiting 16 enrolled Massachusetts General Hospital GlaxoSmithKline · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a randomized, two-arm, open-label, phase 0 trial to assess intratumoral pharmacokinetics and pharmacodynamics of niraparib in subjects with progressive IDH1 or IDH2 mutant glioma. \- This research study involves an experimental treatment called Niraparib.

Timeline

Start
2023-05-18
Primary completion
2026-07
Completion
2026-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Niraparib Small molecule Oral