drugset / Trial / NCT05411107

Oral Iloprost for the Prevention of Lung Cancer In Former Smokers

NCT05411107

RandomizedParallel-groupDouble-blindPrevention

Summary

This phase II trial tests whether oral iloprost works in preventing lung cancer (chemoprevention) in former smokers. Oral iloprost has previously been shown to reduce abnormal lung cells in former smokers, suggesting a clinically significant impact on lung cancer risk. The use of oral iloprost may help keep cancer from forming and reduce abnormal cells in the lung in order to lower the risk of developing lung cancer in former smokers.

Timeline

Start
2024-06-01
Primary completion
2026-12-01
Completion
2027-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Iloprost Other / unclassified 150 ug Oral