drugset / Trial / NCT05411718
A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome
Phase 2
Recruiting
40 enrolled
M.D. Anderson Cancer Center
National Cancer Institute (NCI) · collabNational Institutes of Health (NIH) · collab
RandomizedParallel-groupTriple-blindPrevention
Summary
To learn about the effects of naproxen and aspirin on the normal colon in people with Lynch Syndrome.
Timeline
- Start
- 2023-03-21
- Primary completion
- 2026-11-30
- Completion
- 2026-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Aspirin | Small molecule | — | Oral |
| Subject | Naproxen | Small molecule | — | Oral |