drugset / Trial / NCT05412576

a Pilot Study of Lidocaine Infusion for Postoperative Analgesia in Elderly Patients With Colorectal Cancer Surgery

NCT05412576 ↗

Completed 220 enrolled West China Hospital
RandomizedParallel-groupQuadruple-blindTreatment

Summary

patients who meet the enrollment criteria will be randomized 1:1:1:1 to the different doses of lidocaine or the placebo group. In the lidocaine groups, at the beginning of surgery, lidocaine 0.5mg/kg, 1.0mg/kg, and 1.5mg/kg per hour were continuously infused (using ideal body weight) respectively during the whole procedure. In contrast, the control group was infused with the same dose of normal saline. All the infusion procedures will be stopped at the end of surgery

Timeline

Start
2021-06-01
Primary completion
2022-10-24
Completion
2022-12-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Lidocaine Other / unclassified 0.5 mg/kg Intravenous
Subject Lidocaine Other / unclassified 1 mg/kg Intravenous
Subject Lidocaine Other / unclassified 1.5 mg/kg Intravenous
Subject Lidocaine Other / unclassified 30 mg/kg Intravenous

Indications