drugset / Trial / NCT05413421

Study of ORIC-944 in Patients With Metastatic Prostate Cancer

NCT05413421

Phase 1 Recruiting 275 enrolled ORIC Pharmaceuticals
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to establish the safety and preliminary antitumor activity of ORIC-944 as a single agent and in combinations with ARPIs in patients with metastatic prostate cancer.

Timeline

Start
2022-06-01
Primary completion
2027-06
Completion
2028-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Abiraterone acetate Small molecule 1000 mg Oral
Subject Apalutamide Small molecule 240 mg Oral
Subject Darolutamide Other / unclassified 600 mg Oral
Subject Enzalutamide Other / unclassified 160 mg Oral
Subject ORIC-944 Small molecule Oral