drugset / Trial / NCT05415657
Denosumab Effect on Bone Quality and Function After Lumbar Fusion Surgery
RandomizedParallel-groupTriple-blindTreatment
Summary
Degenerative lumbar spinal diseases have become a common health problem and the most frequent indication for spinal surgery in elderly individuals. It mainly contain lumbar spinal stenosis and spondylolisthesis, occurs in most people over 60 years of age, and patients primarily diagnosed with lumbar degenerative disease are more likely to have osteoporosis. Our study was to explore denosumab effect on bone quality and functional status in osteopenia patients with lumbar degenerative diseases after lumbar fusion surgery.
Timeline
- Start
- 2020-01-12
- Primary completion
- 2023-01-05
- Completion
- 2023-01-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Denosumab | Monoclonal antibody | 60 mg | Subcutaneous |