drugset / Trial / NCT05416021

Relative Bioavailability Trial of Dapivirine Ring-004 and Ring-008

NCT05416021

Phase 1 Completed 124 enrolled International Partnership for Microbicides, Inc.
RandomizedCrossoverOpen-labelPrevention

Summary

A Phase I, Open-Label, Randomized, Crossover Trial to Investigate the Relative Bioavailability of the 25 mg Dapivirine Vaginal Ring-004 inserted every 30 days and 100 mg Dapivirine Vaginal Ring-008 inserted for 90 days in Healthy Female Participants

Timeline

Start
2022-08-01
Primary completion
2024-04-02
Completion
2024-07-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator dapivirine Small molecule 25 mg
Comparator dapivirine Small molecule 100 mg