drugset / Trial / NCT05418556

Tailored Versus Coventional AntiPlaTelet Strategy Intended After OPTIMIZEd Drug Eluting Stent

NCT05418556 ↗

Phase 4 Recruiting 3944 enrolled Asan Medical Center
RandomizedParallel-groupOpen-labelTreatment

Summary

Objectives: To assess the safety of tailored antiplatelet therapy (short DAPT followed by P2Y12 inhibitor alone strategy) in patients who received optimized DES implantation guided by intravascular imaging (IVUS or OCT) Hypothesis: Tailored antiplatelet strategy (short DAPT followed by P2Y12 inhibitor alone) is superior to conventional antiplatelet strategy in terms of clinically relevant bleeding and noninferior for ischemic composite adverse events in patients who received intravascular imaging-guided optimized DES implantation. (Optimized stent evaluated by on-site IVUS/OCT could act as an essential criterion for decision making for tailored antithrombotic strategy)

Timeline

Start
2022-10-21
Primary completion
2027-12-31
Completion
2032-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Aspirin Small molecule — —