drugset / Trial / NCT05425979

Mepivacaine Versus Bupivacaine Onset Time in Ultrasound-guided Ankle Blocks

NCT05425979

Phase 4 Enrolling by invitation 50 enrolled Mayo Clinic
RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this research is to determine if both local anesthetics (mepivacaine and bupivacaine) are similar in their onset of sensory block to assess the efficiency of ultrasound-guided ankle blocks in our practice. Currently it is the standard of care to perform ankles blocks with both mepivacaine and bupivacaine. However, given similarity in their safety profile researchers would like to compare if one is non-inferior to the other in terms of onset time of ankle block.

Timeline

Start
2024-03-11
Primary completion
2026-12-31
Completion
2027-03-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bupivacaine Other / unclassified 0.5 % Other
Comparator Bupivacaine Other / unclassified 30 ml Other
Comparator Mepivacaine Other / unclassified 1.5 % Other
Comparator Mepivacaine Other / unclassified 30 ml Other