drugset / Trial / NCT05431218

Association of Cathelicidin and Vitamin D Levels With the Category and Course of COPD

NCT05431218

Phase 4 Completed 120 enrolled Karaganda Medical University
Non-randomizedParallel-groupOpen-labelSupportive care

Summary

Recruitment of patients with COPD. Assessment of clinical status, determination of vitamin D and cathelicidin levels. In the group with vitamin D deficiency, patients receive cholecalciferol (vitamin D) daily for 3 months. After 3 months, the clinical status was assessed again, the level of vitamin D and cathelicidin was determined. When vitamin D levels normalize, cholecalciferol replacement therapy is discontinued for 3 months. After that, a control inspection and laboratory tests are performed.

Timeline

Start
2020-02-18
Primary completion
2021-12-30
Completion
2021-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cholecalciferol Other / unclassified 4000 iu
Comparator Cholecalciferol Other / unclassified 5000 iu
Comparator Cholecalciferol Other / unclassified 6000 iu
Comparator Cholecalciferol Other / unclassified 7000 iu
Comparator Cholecalciferol Other / unclassified 8000 iu