drugset / Trial / NCT05431218
Association of Cathelicidin and Vitamin D Levels With the Category and Course of COPD
Non-randomizedParallel-groupOpen-labelSupportive care
Summary
Recruitment of patients with COPD. Assessment of clinical status, determination of vitamin D and cathelicidin levels. In the group with vitamin D deficiency, patients receive cholecalciferol (vitamin D) daily for 3 months. After 3 months, the clinical status was assessed again, the level of vitamin D and cathelicidin was determined. When vitamin D levels normalize, cholecalciferol replacement therapy is discontinued for 3 months. After that, a control inspection and laboratory tests are performed.
Timeline
- Start
- 2020-02-18
- Primary completion
- 2021-12-30
- Completion
- 2021-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cholecalciferol | Other / unclassified | 4000 iu | — |
| Comparator | Cholecalciferol | Other / unclassified | 5000 iu | — |
| Comparator | Cholecalciferol | Other / unclassified | 6000 iu | — |
| Comparator | Cholecalciferol | Other / unclassified | 7000 iu | — |
| Comparator | Cholecalciferol | Other / unclassified | 8000 iu | — |