Effect of Coadministration of Itraconazole on the Pharmacokinetics of CRD-740

Summary

This is a Phase 1, single-site, open-label, fixed sequence crossover study to investigate the effect of coadministration of itraconazole on the pharmacokinetics of CRD-740 in healthy male and female subjects. Subjects will be admitted into the study site on Day -1 and will be confined to the study site until discharge on Day 16. Subjects will receive CRD-740 orally on Days 1 and 10. Itraconazole will be given once daily, orally, on Days 7 through 15.

Timeline

Start

2022-06-27

Primary completion

2022-08-03

Completion

2022-08-10

Drugs

Indications