drugset / Trial / NCT05445128

Study of MGTA-145 and Plerixafor in Patients With Sickle Cell Disease

NCT05445128 ↗

Phase 2 Terminated 1 enrolled Ensoma Genetix Biotherapeutics Inc. · collab
Non-randomizedSequentialOpen-labelTreatment

Summary

This research study is designed to investigate a new potential medicine for mobilizing stem cells and apheresis collection in patients with Sickle Cell Disease. MGTA-145, the new potential medicine, will be given with plerixafor.

Timeline

Start
2022-06-24
Primary completion
2022-12-08
Completion
2023-02-02

Outcome

Outcome not reported

Stopped (Business): “This study was voluntarily terminated due to a business decision not to proceed, and not due to any safety issue.”

Drugs

EvaluationDrugModalityDoseRoute
Subject MGTA-145 Protein / enzyme biologic — Intravenous
Subject Plerixafor Small molecule 240 ug/kg Subcutaneous

Indications