drugset / Trial / NCT05450497

Effect of Sedative Agent on Reducing the Frequency of Arrhythmia in the Patients After Cardiac Surgery

NCT05450497 ↗

Completed 356 enrolled Anesthesia Research Group UA
RandomizedParallel-groupOpen-labelPrevention

Summary

Arrhythmias early in the recovery period after cardio thoracic surgery are common they develop in 11 to 40 percent of patients after coronary-artery bypass grafting. The right chose of sedative agent could decrease the level of arrhythmia incidence.

Timeline

Start
2017-07-01
Primary completion
2019-07-01
Completion
2019-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 0.2 ug/kg —
Subject Dexmedetomidine Other / unclassified 0.5 ug/kg —
Subject Dexmedetomidine Other / unclassified 0.7 ug/kg —
Subject Dexmedetomidine Other / unclassified 1 ug/kg —
Subject Propofol Small molecule 0.5 mg/kg —
Subject Propofol Small molecule 1 mg/kg —
Subject Propofol Small molecule 1.5 mg/kg —