drugset / Trial / NCT05451381

Vasopressor Requirements Depends on Sedation Strategy

NCT05451381 ↗

Completed 356 enrolled Anesthesia Research Group UA
RandomizedParallel-groupOpen-labelPrevention

Summary

Most of the patients after cardiac surgery need sedation in the iCU. Sedation strategy could impact the incidence of vasopressor use.

Timeline

Start
2017-08-01
Primary completion
2022-05-01
Completion
2022-05-29

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 0.2 ug/kg —
Subject Dexmedetomidine Other / unclassified 0.5 ug/kg —
Subject Dexmedetomidine Other / unclassified 0.7 ug/kg —
Subject Dexmedetomidine Other / unclassified 1 ug/kg —
Subject Propofol Small molecule 0.5 mg/kg —
Subject Propofol Small molecule 1 mg/kg —
Subject Propofol Small molecule 1.5 mg/kg —