Pharmacokinetics and Excretion of Albendazole and Its Metabolites in Saliva

Summary

This project will develop and assess the feasibility and acceptability of a salive-based assay to monitor adherence to Mass Drug Administration (MDA) campaigns within Soil-transmitted helminthiasis (STH) control programs, evaluating the salive and serum pharmacokinetics of ALBENDAZOLE (ABZ) and its metabolites.The final goal is to obtain a field ready tool for the measurement of adherence to anthelmintic treatment at a community level that serves as a coverage/adherence indicator and a reference standard for other monitoring tools.

Timeline

Start

2022-07-18

Primary completion

2022-08-30

Completion

2022-12-16

Drugs

Indications

No indication recorded.