drugset / Trial / NCT05455294
Combination Navitoclax, Venetoclax and Decitabine for Advanced Myeloid Neoplasms
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this research study is to test the safety of a new three drug combination of navitoclax, decitabine, and venetoclax to treat advanced myeloid malignancies. The names of the drugs involved in this study are: * Venetoclax * Decitabine * Navitoclax
Timeline
- Start
- 2022-07-18
- Primary completion
- 2024-04-17
- Completion
- 2026-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Decitabine | Small molecule | — | Intravenous |
| Subject | Navitoclax | Small molecule | — | Oral |
| Subject | Venetoclax | Small molecule | — | Oral |