drugset / Trial / NCT05477875
Cannabinoid vs Opioid for Photorefractive Keratectomy Pain Control
Phase 2
Completed
35 enrolled
University of Florida
Consortium for Medical Marijuana Clinical Outcomes Research · collab
RandomizedCrossoverOpen-labelTreatment
Summary
Photorefractive Keratectomy (PRK) is a commonly performed corneal refractive surgery but has significant post-operative pain. Pain medications after PRK are typically opioid-acetaminophen combinations. Alternatives to opioid medication are worth consideration. Patients will receive PRK in each eye sequentially, using the cannabinoid or codeine/acetaminophen for one eye and the other treatment for the fellow eye two weeks later.
Timeline
- Start
- 2024-02-01
- Primary completion
- 2025-01-22
- Completion
- 2025-01-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetaminophen | Small molecule | 300 mg | Oral |
| Subject | Codeine | Small molecule | 30 mg | Oral |
| Subject | Dronabinol | Other / unclassified | — | Oral |