drugset / Trial / NCT05513976
Clinical Study of SHR4640 Tablets Combined With Febuxostat Tablets in the Treatment of Primary Gout and Hyperuricemia
RandomizedParallel-groupQuadruple-blindTreatment
Summary
SHR4640 tablets is a highly selective and potent URAT1 inhibitors,study number is SHR4640-203. The primary purpose of the study is to evaluate the efficacy and safety of the combination of SHR4640 and febuxostat compared with placebo and febuxostat in primary gout and hyperuricemia subjects with inadequate control on febuxostat for 12 weeks.
Timeline
- Start
- 2022-09-15
- Primary completion
- 2023-05-30
- Completion
- 2023-09-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | SHR4640 | Small molecule | 5 mg | — |
| Subject | SHR4640 | Small molecule | 10 mg | — |
| Background | Febuxostat | Small molecule | 40 mg | — |
| Background | Febuxostat | Small molecule | 60 mg | — |
| Background | Febuxostat | Small molecule | 80 mg | — |