drugset / Trial / NCT05515809

Evaluation of the Effect of Para-sternal Block on Postoperative Respiratory Function After Cardiac Sternotomy Surgery

NCT05515809

Phase 3 Active not recruiting 84 enrolled Centre Hospitalier Universitaire, Amiens
RandomizedParallel-groupOpen-labelTreatment

Summary

Postoperative pain after cardiac surgery is associated with reduced postoperative respiratory function. There is an association between greater pain and more pronounced decreases in lung volumes postoperatively. With an incidence of 10% to 25% of cases, pulmonary complications are the second source of postoperative morbidity after cardiac complications; in 2-5% of cases, the dysfunction is severe and leads to significant consequences that can lead to death. It has been shown that postoperative pain after cardiac surgery is associated with a reduction in functional respiratory capacity. There is an association between greater pain and more pronounced decreases in lung volumes postoperatively. The main objective of this study will be to evaluate the impact of locoregional anesthesia by parasternal block analgesic on postoperative respiratory function at D1 postoperatively

Timeline

Start
2022-07-19
Primary completion
2025-06
Completion
2025-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Ropivacaine Other / unclassified 0.2 % Other
Subject Ropivacaine Other / unclassified 2 mg/ml Other
Subject Ropivacaine Other / unclassified 20 ml Other
Comparator Morphine Other / unclassified

Indications

No indication recorded.