drugset / Trial / NCT05520645
Etomidate Induction in Hysteroscopic Surgery
RandomizedParallel-groupDouble-blindTreatment
Summary
This study intends to study the optimal dose induced by etomidate in outpatients undergoing painless hysteroscopic surgery. At present, the dosage in the user manual is 0.1-0.3mg/kg. In clinical use, it is found that 0.1mg/kg often fails to achieve sedative effect, and 0.3mg/kg is prone to muscle twitching. Therefore, three groups of doses of 0.15mg/kg, 0.2mg/kg and 0.25mg/kg are set. It is hoped that this study will provide a basis for clinical evaluation of etomidate in anesthesia induction of hysteroscopic surgery.
Timeline
- Start
- 2022-08-25
- Primary completion
- 2023-09-30
- Completion
- 2023-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Etomidate | Small molecule | 0.15 mg/kg | — |
| Subject | Etomidate | Small molecule | 0.2 mg/kg | — |
| Subject | Etomidate | Small molecule | 0.25 mg/kg | — |
| Comparator | Propofol | Small molecule | 2 mg/kg | — |
Indications
No indication recorded.