drugset / Trial / NCT05533697

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

NCT05533697 ↗

Phase 1/2 Recruiting 361 enrolled ModernaTX, Inc.
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The primary goal of this study is to assess the safety and tolerability of mRNA-4359 administered alone and in combination with pembrolizumab or ipilimumab and nivolumab.

Timeline

Start
2022-09-01
Primary completion
2032-02-18
Completion
2032-02-18

Drugs

EvaluationDrugModalityDoseRoute
Subject Ipilimumab Monoclonal antibody — Intravenous
Subject Nivolumab Monoclonal antibody — Intravenous
Subject Pembrolizumab Monoclonal antibody — Intravenous
Subject mRNA-4359 Unknown — Intramuscular

Indications