drugset / Trial / NCT05538741

Hypotension After Anesthetic Induction with Remimazolam in Elderly

NCT05538741

Completed 62 enrolled Kangbuk Samsung Hospital
RandomizedParallel-groupTriple-blindOther

Summary

Even though remimazolam is known to be safely administered without hemodynamic instability, hypotension is the one of the common side effects of remimazolam. Because elderly patients are susceptible to hypotension due to old age, multimodality, and multiple medications, hypotension can be harmful in elderly patients. Remimazolam can be administered either bolus or continuous for anesthetic induction. In our study the investigators aimed to compare the incidence of hypotension after anesthetic induction using remimazolam by bolus injection and continuous infusion in elderly patients.

Timeline

Start
2023-07-14
Primary completion
2024-06-14
Completion
2024-06-14

Drugs

EvaluationDrugModalityDoseRoute
Subject Remimazolam Small molecule 0.14 mg/kg
Subject Remimazolam Small molecule 0.19 mg/kg
Subject Remimazolam Small molecule 0.25 mg/kg
Subject Remimazolam Small molecule 12 mg/kg

Indications